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逆轉(zhuǎn)錄酶（RTs）是用于從RNA模板生成互補(bǔ)DNA（cDNA）的酶，該過程稱為逆轉(zhuǎn)錄。 逆轉(zhuǎn)錄酶（RTs）使用RNA模板和與RNA 3'末端互補(bǔ)的短引物指導(dǎo)第一鏈cDNA的合成。 核苷逆轉(zhuǎn)錄酶抑制劑（NRTIs）阻斷逆轉(zhuǎn)錄酶（一種HIV酶）。 非核苷逆轉(zhuǎn)錄酶抑制劑（NNRTIs）結(jié)合并阻斷HIV逆轉(zhuǎn)錄酶。 HIV使用逆轉(zhuǎn)錄酶將其RNA轉(zhuǎn)化為DNA（逆轉(zhuǎn)錄）。 阻斷逆轉(zhuǎn)錄酶和逆轉(zhuǎn)錄阻止HIV復(fù)制。 Reverse transcriptases (RTs) are enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcriptases (RTs) use an RNA template and a short primer complementary to the 3' end of the RNA to direct the synthesis of the first strand cDNA. Nucleoside reverse transcriptase inhibitors (NRTIs) block reverse transcriptase (an HIV enzyme). Non-nucleoside reverse transcriptase inhibitors (NNRTIs) bind to and block HIV reverse transcriptase. HIV uses reverse transcriptase to convert its RNA into DNA (reverse transcription). Blocking reverse transcriptase and reverse transcription prevents HIV from replicating.