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ICA

NMR下載 COA and HPLC MSDS下載
names：
ICA
CAS號：
3374-88-7
MDL Number： MFCD00642222
MF(分子式)： C13H10N4S MW(分子量)： 254.31
EINECS: Reaxys Number:
Pubchem ID:772885 Brand:BIOFOUNT

ICA(3374-88-7)是SK通道 (SK channel) 抑制劑。ICA有抗利什曼原蟲活性

貨品編碼	規(guī)格	純度	價格 (￥)	現(xiàn)價(￥)	特價(￥)	庫存描述	數(shù)量	總計 (￥)
YZM000799-5mg	5mg	99.6%	￥ 4556.00	￥ 4556.00		2-3天	- +	￥ 0.00
YZM000799-1mg	1mg	99.6%	￥ 1462.00	￥ 1462.00		2-3天	- +	￥ 0.00

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中文別名	ICA(3374-88-7);TCMDC-124275;GNF-PF-4773;Pyridin-2-yl-(4-pyridin-2-yl-thiazol-2-yl)-amine
英文別名	ICA,3374-88-7
CAS號	3374-88-7
Inchi	InChI=1S/C13H10N4S/c1-3-7-14-10(5-1)11-9-18-13(16-11)17-12-6-2-4-8-15-12/h1-9H,(H,15,16,17)
InchiKey	RYCUBTFYRLAMFA-UHFFFAOYSA-N
分子式 Formula	C13H10N4S
分子量 Molecular Weight	254.31
溶解度Solubility	生物體外In Vitro:DMSO溶解度≥ 49.5 mg/mL(194.64 mM)*"≥" means soluble可溶, but saturation unknown溶解度未知.
性狀	淺棕色至棕色固體粉末
儲藏條件 Storage conditions	storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)

ICA(3374-88-7)實驗注意事項：
1.實驗前需戴好防護眼鏡，穿戴防護服和口罩，佩戴手套，避免與皮膚接觸。
2.實驗過程中如遇到有毒或者刺激性物質及有害物質產(chǎn)生，必要時實驗操作需要手套箱內完成以免對實驗人員造成傷害
3.實驗后產(chǎn)生的廢棄物需分類存儲，并交于專業(yè)生物廢氣物處理公司處理，以免造成環(huán)境污染

ICA(3374-88-7) Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

Tag:ICA(3374-88-7),ICA試劑,ICA抑制劑,ICA的純度,ICA的作用,ICA的外觀,ICA的合成,ICA的用途,ICA的廠家,ICA的溶解度,ICA的價格,ICA的生產(chǎn),ICA的MSDS,ICA的使用,ICA的注意事項

產(chǎn)品說明	ICA(3374-88-7)是SK通道 (SK channel) 抑制劑。ICA有抗利什曼原蟲活性
Introduction	ICA (3374-88-7) is an SK channel inhibitor. ICA has anti-leishmania activity
Application1
Application2
Application3

警示圖
危險性	warning
危險性警示	Not available
安全聲明	H303吞入可能有害+H313皮膚接觸可能有害+H2413吸入可能對身體有害
安全防護	P264處理后徹底清洗+P280戴防護手套/穿防護服/戴防護眼罩/戴防護面具+P305如果進入眼睛+P351用水小心沖洗幾分鐘+P338取出隱形眼鏡（如果有）并且易于操作,繼續(xù)沖洗+P337如果眼睛刺激持續(xù)+P2393獲得醫(yī)療建議/護理
備注	實驗過程中防止吸入、食入，做好安全防護

Antiarrhythmic effect of the Ca2+-activated K+ (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

Pharmacological blockade of small conductance Ca2+-activated K+ channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

Theory of magnetism close to the5\nT\n2 —1\nA\n1 crossover in iron(II) complexes(Theoretica chimica acta,1971)

Magnetic properties of iron(II) complex with 2-(pyridin-2-ylamino)-4-(pyridin-2-yl)thiazole(Magnetic Properties of Paramagnetic Compounds,2017)

Small-conductance Ca2+-activated K+ channels: insights into their roles in cardiovascular disease(Experimental & Molecular Medicine,2018)

Towards Control of the Intrinsic Characteristics of Spin-Crossover in Ferrous Materials
Abstract:Metal complexes exhibiting spin-crossover between low-spin (LS) and high-spin (HS) electronic states have been recognized since Cambi, Szegö and Cagnasso first observed “magnetic isomerism” for tris(dithiocarbamato) iron(III) complexes in 1931 [1]. Today, about 100 spin-crossover systems are known and the field has developed into an important area of contemporary coordination chemistry spanning from theory to applications and based upon ligand design and elaborated physicochemical studies of the resulting complexes.

Spin transition in iron(II) complexes induced by heat, pressure, light, and nuclear decay
Abstract:The phenomenon of temperature-dependent spin transition will be introduced and the numerous chemical and physical influences affecting the spin transition characteristics will be discussed. We shall mainly concentrate on the spin crossover system [Fe(2-pic)3]X2·Sol (2-pic=2-aminomethylpyridine; X=Cl, Br; Sol=C2H5OH, CH3OH) and demonstrate how the behaviour of the spin transition5T2g(Oh)?1A1g(Oh) is influenced by substituting the metalion, the non-coordinating anions X, the crystal solvent molecules Sol and by isotopic exchange with H/D and14N/15N. It will also be shown that the spin transition is very susceptible to pressure. A quantitative spin state conversion from low spin to high spin can also be achieved by illuminating the crystals of a spin crossover system at sufficiently low temperatures. The metastable quintet state can be trapped with practically infinite lifetimes. Several examples for this “Light-Induced Excited Spin State Trapping” (LIESST) will be given. Finally, the occurrence of short-lived anomalous spin quintet states following the57Co(EC)57Fe nuclear decay, which have been observed in the Mössbauer emission spectra of57Co-doped complex compounds, will be discussed with particular references to the LIESST effect.

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