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33401-94-4
  • 酒石酸噻吩嘧啶

  • names:

    Pyrantel tartrate

  • CAS號(hào):

    33401-94-4

    MDL Number:
  • MF(分子式): C15H20N2O6S MW(分子量): 356.39
  • EINECS:251-501-8 Reaxys Number:33401-94-4
  • Pubchem ID:5145916 Brand:BIOFOUNT
酒石酸噻吩嘧啶
酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4):牲畜的廣譜驅(qū)蟲藥。
貨品編碼 規(guī)格 純度 價(jià)格 (¥) 現(xiàn)價(jià)(¥) 特價(jià)(¥) 庫(kù)存描述 數(shù)量 總計(jì) (¥)
YZM000792-500mg 500mg 99.58% ¥ 911.00 ¥ 911.00 2-3天
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0.00
YZM000792-100mg 100mg 99.58% ¥ 341.25 ¥ 341.25 2-3天
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中文別名 酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)
英文別名 Pyrantel tartrate(酒石酸噻吩嘧啶,33401-94-4)
CAS號(hào) 33401-94-4
Inchi InChI=1S/C11H14N2S.C4H6O6/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10;5-1(3(7)8)2(6)4(9)10/h2,4-6,9H,3,7-8H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/b6-5+;/t;1-,2-/m.1/s1
InchiKey VWRCYAZJKNPEQR-NIEARKAZSA-N
分子式 Formula C15H20N2O6S
分子量 Molecular Weight 356.39
溶解度Solubility 生物體外In Vitro:DMSO溶解度≥ 34 mg/mL(95.40 mM)*"≥" means soluble可溶, but saturation unknown溶解度未知.
性狀 固體粉末,Power
儲(chǔ)藏條件 Storage conditions -20°C 3 years年 4°C 2 years年 / In solvent溶液中:-80°C 6 months月 -20°C 1 month月
酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)毒性
生物 測(cè)試類型 路線 報(bào)告劑量(標(biāo)準(zhǔn)化劑量) 影響 參考
cattle LD unreported > 200mg/kg (200mg/kg)   Australian Veterinary Journal. Vol. 46, Pg. 297, 1970.
mouse LD50 intravenous 2220ug/kg (2.22mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
mouse LD50 oral 123mg/kg (123mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
mouse LD50 subcutaneous > 25mg/kg (25mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
rat LD50 oral 170mg/kg (170mg/kg)   Australian Veterinary Journal. Vol. 46, Pg. 297, 1970.

酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)實(shí)驗(yàn)注意事項(xiàng):
1.實(shí)驗(yàn)前需戴好防護(hù)眼鏡,穿戴防護(hù)服和口罩,佩戴手套,避免與皮膚接觸。
2.實(shí)驗(yàn)過程中如遇到有毒或者刺激性物質(zhì)及有害物質(zhì)產(chǎn)生,必要時(shí)實(shí)驗(yàn)操作需要手套箱內(nèi)完成以免對(duì)實(shí)驗(yàn)人員造成傷害
3.實(shí)驗(yàn)后產(chǎn)生的廢棄物需分類存儲(chǔ),并交于專業(yè)生物廢氣物處理公司處理,以免造成環(huán)境污染Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tag:酒石酸噻吩嘧啶MSDS,酒石酸噻吩嘧啶蒸汽壓,酒石酸噻吩嘧啶合成,酒石酸噻吩嘧啶標(biāo)準(zhǔn),酒石酸噻吩嘧啶應(yīng)用,酒石酸噻吩嘧啶合成,酒石酸噻吩嘧啶沸點(diǎn),酒石酸噻吩嘧啶閃點(diǎn),酒石酸噻吩嘧啶用途,酒石酸噻吩嘧啶溶解度,酒石酸噻吩嘧啶價(jià)格,酒石酸噻吩嘧啶作用,酒石酸噻吩嘧啶結(jié)構(gòu)式,酒石酸噻吩嘧啶用處,酒石酸噻吩嘧啶毒理性質(zhì),酒石酸噻吩嘧啶物理性質(zhì)
產(chǎn)品說明 酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)是一種殺線蟲噻吩
IntroductionPyrantel tartrate(酒石酸噻吩嘧啶,33401-94-4) is an antinematodal thiophene
Application1
Application2
Application3
Parasite field study in central Kentucky on thoroughbred foals (born in 2004) treated with pyrantel tartrate daily and other parasiticides periodically Parasitology Research 2006/PMID: 17013652
Serum Strongylus vulgaris-specific antibody responses to anthelmintic treatment in naturally infected horses Parasitology Research 2014/PMID: 25358238
A light and electron microscopic study on the synergistic effect of pyrantel and the febantel metabolite febendazole on adult Toxocara canis in vitro Parasitology Research 2003/PMID: 12684883
Diagnosis and control of anthelmintic-resistant Parascaris equorum Parasites & Vectors 2009/PMID: 19778469
Transient effects of levamisole on Brugia malayi microfilariae Invertebrate Neuroscience 2015/PMID: 26187649

Activity of selected antioxidative enzymes in rats exposed to dimethoate and pyrantel tartrate

Abstract

This study presents the results of research concerning the effect of single and combined application of pyrantel tartrate and dimethoate on selected antioxidative enzymes: catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx), in rat erythrocytes. Pyrantel tartrate was applied twice, at a dose of 85 mg/kg bw at a two week interval, i.e. on day 14 and 28 of the experiment, orally, in a water solution with a stomach tube. Dimethoate was administered with drinking water for 28 days at a dose of 25 mg/kg bw/day. It was found that pyrantel tartrate caused only small changes in the activity of the antioxidative enzymes under analysis. Subchronic exposure of rats to dimethoate caused a significant increase in the activity of CAT, SOD and GPx in erythrocytes, indicating the existence of strong oxidative stress. In combined intoxication, no significant effects of administering pyrantel tartrate on the activity of CAT, SOD and GPx was found in animals poisoned with dimethoate. The profile of changes was similar to that observed in rats exposed only to the organophosphorus insecticide. This may indicate a lack of interaction between the compounds used in the experiment.

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