購物車 
-
PNU-176798
- names：
PNU-176798
- CAS號：
428861-91-0
MDL Number： - MF(分子式)： C16H13FN4O3S MW(分子量)： 360.36
- EINECS: Reaxys Number:
- Pubchem ID:10338562 Brand:BIOFOUNT
PNU-176798（428861-91-0）是一種抗菌劑，靶向多種革蘭氏陽性和厭氧細菌中的蛋白質合成。
| 貨品編碼 | 規(guī)格 | 純度 | 價格 (￥) | 現(xiàn)價(￥) | 特價(￥) | 庫存描述 | 數(shù)量 | 總計 (￥) |
|---|---|---|---|---|---|---|---|---|
| YZM000402-1mg | 1mg | >97% | ￥ 9155.00 | ￥ 9155.00 | Backorder | ￥ 0.00 |
| 中文別名 | PNU-176798(428861-91-0) |
| 英文別名 | PNU-176798(428861-91-0),PNU176798,PNU 176798,N-[[(5S)-3-[4-(5-Cyano-1,3-thiazol-2-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide |
| CAS號 | 428861-91-0 |
| Inchi | InChI=1S/C16H13FN4O3S/c1-9(22)19-6-11-8-21(16(23)24-11)10-2-3-13(14(17)4-10)15-20-7-12(5-18)25-15/h2-4,7,11H,6,8H2,1H3,(H,19,22)/t11-/m0/s1 |
| InchiKey | FGUCVLMMGZZQBB-NSHDSACASA-N |
| 分子式 Formula | C16H13FN4O3S |
| 分子量 Molecular Weight | 360.36 |
| 溶解度Solubility | |
| 性狀 | Solid |
| 儲藏條件 Storage conditions | 請根據(jù)產(chǎn)品建議的存儲條件進行存儲,Please store the product under the recommended condition sin the description. |
PNU-176798(CAS:428861-91-0)實驗注意事項：
1.實驗前需戴好防護眼鏡，穿戴防護服和口罩，佩戴手套，避免與皮膚接觸。
2.實驗過程中如遇到有毒或者刺激性物質及有害物質產(chǎn)生，必要時實驗操作需要手套箱內(nèi)完成以免對實驗人員造成傷害
3.實驗后產(chǎn)生的廢棄物需分類存儲，并交于專業(yè)生物廢氣物處理公司處理，以免造成環(huán)境污染Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tag:PNU-176798蒸汽壓,PNU-176798合成,PNU-176798標準,PNU-176798應用,PNU-176798合成,PNU-176798沸點,PNU-176798閃點,PNU-176798用途,PNU-176798溶解度,PNU-176798價格,PNU-176798作用,PNU-176798結構式
1.實驗前需戴好防護眼鏡，穿戴防護服和口罩，佩戴手套，避免與皮膚接觸。
2.實驗過程中如遇到有毒或者刺激性物質及有害物質產(chǎn)生，必要時實驗操作需要手套箱內(nèi)完成以免對實驗人員造成傷害
3.實驗后產(chǎn)生的廢棄物需分類存儲，并交于專業(yè)生物廢氣物處理公司處理，以免造成環(huán)境污染Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tag:PNU-176798蒸汽壓,PNU-176798合成,PNU-176798標準,PNU-176798應用,PNU-176798合成,PNU-176798沸點,PNU-176798閃點,PNU-176798用途,PNU-176798溶解度,PNU-176798價格,PNU-176798作用,PNU-176798結構式
| 產(chǎn)品說明 | PNU-176798(428861-91-0)是一種抗菌劑，可在廣泛的移殖性和厭氧性細菌中靶向蛋白質合成。 |
| Introduction | PNU-176798(428861-91-0)is an antimicrobial agent, targeting protein synthesis in a wide spectrum of gramositive and anaerobic bacteria. |
| Application1 | |
| Application2 | |
| Application3 |
| 警示圖 | |
| 危險性 | warning |
| 危險性警示 | Not available |
| 安全聲明 | H303吞入可能有害+H313皮膚接觸可能有害+H2413吸入可能對身體有害 |
| 安全防護 | P264處理后徹底清洗+P280戴防護手套/穿防護服/戴防護眼罩/戴防護面具+P305如果進入眼睛+P351用水小心沖洗幾分鐘+P338取出隱形眼鏡（如果有）并且易于操作,繼續(xù)沖洗+P337如果眼睛刺激持續(xù)+P2393獲得醫(yī)療建議/護理 |
| 備注 | 實驗過程中防止吸入、食入，做好安全防護 |
| Resistance to Linezolid Antimicrobial Drug Resistance 2009 |
1.Resistance to Linezolid
Abstract:The fi rst description of oxazolidinones as antibacterials was reported by researchers from the DuPont company in 1987. Compounds Dup-105 and DuP-721 (Fig. 1) were introduced as clinical candidates with good activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus, in an in vivo animal effi cacy model (1). These compounds demonstrated lethal toxicity in animal models and were not further developed (2). Researchers at Pharmacia (now Pfi zer) became interested in these molecules and began a chemistry/screening effort to improve the in vitro, in vivo, and safety profi les of oxazolidinones.
Abstract:The fi rst description of oxazolidinones as antibacterials was reported by researchers from the DuPont company in 1987. Compounds Dup-105 and DuP-721 (Fig. 1) were introduced as clinical candidates with good activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus, in an in vivo animal effi cacy model (1). These compounds demonstrated lethal toxicity in animal models and were not further developed (2). Researchers at Pharmacia (now Pfi zer) became interested in these molecules and began a chemistry/screening effort to improve the in vitro, in vivo, and safety profi les of oxazolidinones.
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