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Ungeremine acetate

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names：
(1,3)Dioxolo(4,5-j)pyrrolo(3,2,1-de)phenanthridinium, 4,5-dihydro-2-hydroxy-, acetate
CAS號(hào)：
61221-41-8
MDL Number：
MF(分子式)： C18H15NO5 MW(分子量)： 325.32
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	(1,3)Dioxolo(4,5-j)pyrrolo(3,2,1-de)phenanthridinium, 4,5-dihydro-2-hydroxy-, acetate
英文別名	AT-1840; AT 1840; AT1840; Ungeremine acetate; Lycobetaine acetate;
CAS號(hào)	61221-41-8
Inchi	InChI=1S/C16H11NO3.C2H4O2/c18-11-3-9-1-2-17-7-10-4-14-15(20-8-19-14)6-12(10)13(5-11)16(9)17;1-2(3)4/h3-7H,1-2,8H2;1H3,(H,3,4)
InchiKey	HKIJKEFVQKXWGW-UHFFFAOYSA-N
分子式 Formula	C18H15NO5
分子量 Molecular Weight	325.32
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Ungeremine acetate(CAS:61221-41-8 ):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類(lèi)或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Ungeremine, also known as AT-1840, is a betaine-type alkaloid isolated from Nerine bowdenii and related plants such as Pancratium maritimum. Pharmacologically, it is of interest as an acetylcholinesterase inhibitor and accordingly as possibly relevant to Alzheimer's disease. It also has been investigated as a bactericide.
Application1
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危險(xiǎn)性	Warning
危險(xiǎn)性警示
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[1]Moeini A, Cimmino A, Dal Poggetto G, Di Biase M, Evidente A, Masi M, Lavermicocca P, Valerio F, Leone A, Santagata G, Malinconico M. Effect of pH and TPP concentration on chemico-physical properties, release kinetics and antifungal activity of Chitosan-TPP-Ungeremine microbeads. Carbohydr Polym. 2018 Sep 1;19

5:631-641. doi: 10.1016/j.carbpol.2018.05.005. Epub 2018 May 4. PubMed PMID: 29805021.

[3]Valerio F, Masi M, Cimmino A, Moeini SA, Lavermicocca P, Evidente A. Antimould microbial and plant metabolites with potential use in intelligent food packaging. Nat Prod Res. 2018 Jul;32(13):1605-1610. doi: 10.1080/14786419.2017.1385018. Epub 2017 Oct 13. PubMed PMID: 29027475.

[4]Chen T, Gong T, Zhao T, Fu Y, Zhang Z, Gong T. A comparison study between lycobetaine-loaded nanoemulsion and liposome using nRGD as therapeutic adjuvant for lung cancer therapy. Eur J Pharm Sci. 2018 Jan 1;111:293-302. doi: 10.1016/j.ejps.2017.09.041. Epub 2017 Sep 28. PubMed PMID: 28966099.

[5] Chen T, Song X, Gong T, Fu Y, Yang L, Zhang Z, Gong T. nRGD modified lycobetaine and octreotide combination delivery system to overcome multiple barriers and enhance anti-glioma efficacy. Colloids Surf B Biointerfaces. 2017 Aug 1;15

6:330-339. doi: 10.1016/j.colsurfb.2017.05.038. Epub 2017 May 15. PubMed PMID: 28544965.

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