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Dasolampanel

NMR下載 COA and HPLC MSDS下載
names：
(3S,4aS,6S,8aR)-6-(3-chloro-2-(1H-tetrazol-5-yl)phenoxy)-decahydroisoquinoline-3-carboxylic acid
CAS號：
503294-13-1
MDL Number：
MF(分子式)： C17H20ClN5O3 MW(分子量)： 377.829
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Dasolampanel
英文別名	NGX-426; NGX 426; NGX426; Dasolampanel
CAS號	503294-13-1
Inchi	InChI=1S/C17H20ClN5O3/c18-12-2-1-3-14(15(12)16-20-22-23-21-16)26-11-5-4-9-8-19-13(17(24)25)7-10(9)6-11/h1-3,9-11,13,19H,4-8H2,(H,24,25)(H,20,21,22,23)/t9-,10+,11-,13-/m0/s1
InchiKey	LAKQPSQCICNZII-NOHGZBONSA-N
分子式 Formula	C17H20ClN5O3
分子量 Molecular Weight	377.829
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說明	Dasolampanel(CAS:503294-13-1 ):僅限應(yīng)用于工業(yè)或者科學(xué)研究過程中非醫(yī)療目的，不應(yīng)用于人類或動物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。
Introduction	Dasolampanel, also known as NGX-426, is an orally bioavailable analog of tezampanel and thereby competitive antagonist of the AMPA and kainate receptors which was under development for the treatment of chronic pain conditions including neuropathic pain and migraine. It was developed as a follow-on compound to tezampanel, as tezampanel is not bioavailable orally and must be administered by intravenous injection, but ultimately neither drug was ever marketed.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護
備注

[1]Wallace MS, Lam V, Schettler J. NGX426, an oral AMPA-kainate antagonist, iseffective in human capsaicin-induced pain and hyperalgesia. Pain Med. 2012Dec;13(12):1601-10. doi: 10.1111/j.1526-4637.2012.01509.x. Epub 2012 Oct 30.PubMed PMID: 23110368.