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葡萄糖二酸鈣

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names：
Glucaric acid calcium salt (Calcium saccharate), beta-glucuronidase inhibitor
CAS號(hào)：
5793-89-5
MDL Number：
MF(分子式)： C6H16CaO12 MW(分子量)： 320.26
EINECS:611-592-0 Reaxys Number:
Pubchem ID:11954337 Brand:BIOFOUNT

葡萄糖二酸鈣(5793-89-5,Glucaric acid calcium salt)是一種β-葡萄糖醛酸酶抑制劑，可以刺激分化和抑制增殖，顯示體內(nèi)的化學(xué)預(yù)防和抗腫瘤作用。

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中文別名	葡萄糖二酸鈣(5793-89-5);Calcium saccharate;葡萄糖酸鈣鹽;β-葡萄糖醛酸酶抑制劑
英文別名	Glucaric acid calcium salt (Calcium saccharate), beta-glucuronidase inhibitor(5793-89-5);Calcium D-saccharate tetrahydrate; L-Gularic Acid;
CAS號(hào)	5793-89-5
Inchi	InChI=1S/C6H10O8.Ca.4H2O/c7-1(3(9)5(11)12)2(8)4(10)6(13)14;;;;;/h1-4,7-10H,(H,11,12)(H,13,14);;4*1H2/q;+2;;;;/p-2/t1-,2-,3-,4+;;;;;/m0...../s1
InchiKey	ZQWFSIZRQANUDA-WQMSYZFBSA-L
分子式 Formula	C6H16CaO12
分子量 Molecular Weight	320.26
溶解度Solubility
性狀	白色至灰白色固體粉末
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	葡萄糖二酸鈣(5793-89-5,Glucaric acid calcium salt)僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Calcium saccharate is an oxidized non-cyclic hexose sugar. It may inhibit carcinogenesis and proliferation of cancer cells.
Application1
Application2
Application3

警示圖
危險(xiǎn)性	Warning
危險(xiǎn)性警示	P264處理后徹底清洗+P280戴防護(hù)手套/穿防護(hù)服/戴防護(hù)眼罩/戴防護(hù)面具+P305如果進(jìn)入眼睛+P351用水小心沖洗幾分鐘+P338取出隱形眼鏡（如果有）并且易于操作,繼續(xù)沖洗+P337如果眼睛刺激持續(xù)+P313獲得醫(yī)療建議/護(hù)理
安全聲明	H315 H319 H335
安全防護(hù)	P264 P302+P352 P304+P340 P305+P351+P338 P332+P313 P337+P313
備注

[1]Garcia AC, Vavrusova M, Skibsted LH. Calcium d-Saccharate: Aqueous Solubility, Complex Formation, and Stabilization of Supersaturation. J Agric Food Chem. 2016 Mar 23;64(11):2352-60. doi: 10.1021/acs.jafc.6b00166. Epub 2016 Mar 9. PubMed PMID: 26934422.

[2]Agarwal R, Kusek JW, Pappas MK. A randomized trial of intravenous and oral iron in chronic kidney disease. Kidney Int. 2015 Oct;88(4):905-14. doi: 10.1038/ki.2015.163. Epub 2015 Jun 17. PubMed PMID: 26083656; PubMed Central PMCID: PMC4589436.

[3] Calcium-D-glucarate. Altern Med Rev. 2002 Aug;7(4):336-9. Review. PubMed PMID: 12197785.

[4] Wang C, Graham DJ, Kane RC, Xie D, Wernecke M, Levenson M, MaCurdy TE, Houstoun M, Ryan Q, Wong S, Mott K, Sheu TC, Limb S, Worrall C, Kelman JA, Reichman ME. Comparative Risk of Anaphylactic Reactions Associated With Intravenous Iron Products. JAMA. 2015 Nov 17;314(19):2062-8. doi: 10.1001/jama.2015.15572. PubMed PMID: 26575062.

[5] Shi Q, Leng W, Wazir R, Li J, Yao Q, Mi C, Yang J, Xing A. Intravenous Iron Sucrose versus Oral Iron in the Treatment of Pregnancy with Iron Deficiency Anaemia: A Systematic Review. Gynecol Obstet Invest. 2015;80(3):170-8. doi: 10.1159/000376577. Epub 2015 Mar 25. Review. PubMed PMID: 25824489.

6: Macdougall IC, Strauss WE, McLaughlin J, Li Z, Dellanna F, Hertel J. A randomized comparison of ferumoxytol and iron sucrose for treating iron deficiency anemia in patients with CKD. Clin J Am Soc Nephrol. 2014 Apr;9(4):705-12. doi: 10.2215/CJN.05320513. Epub 2014 Jan 23. PubMed PMID: 24458078; PubMed Central PMCID: PMC3974353.7: Pieracci FM, Stovall RT, Jaouen B, Rodil M, Cappa A, Burlew CC, Holena DN, Maier R, Berry S, Jurkovich J, Moore EE. A multicenter, randomized clinical trial of IV iron supplementation for anemia of traumatic critical illness*. Crit Care Med. 2014 Sep;42(9):2048-57. doi: 10.1097/CCM.0000000000000408. PubMed PMID: 24797376.8: Jiang J, Li Y, Feng Z, Yang Y, Zhang P. Glucaric acids from Leonurus japonicus. Fitoterapia. 2015 Dec;107:85-9. doi: 10.1016/j.fitote.2015.10.007. Epub 2015 Oct 23. PubMed PMID: 26526024.9: Qiu Y, Fang F, Du G, Chen J. [Progress in glucaric acid]. Sheng Wu Gong Cheng Xue Bao. 2015 Apr;31(4):481-90. Review. Chinese. PubMed PMID: 26380405.10: Rebel A, Beck A, Efron P, Bavry AA, Ang D. Successful Rescue Therapy for Severe Acute Anemia: Managing the Critically Ill Jehovah's Witness. Am Surg. 2015 Jun;81(6):E263-5. PubMed PMID: 26031262.1

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