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(±)-γ-Tocopherol

NMR下載 COA and HPLC MSDS下載
names：
3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
CAS號：
7616-22-0
MDL Number：
MF(分子式)： C28H48O2 MW(分子量)： 416.69
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
英文別名	(±)-γ-Tocopherol, 7,8-Dimethyltocol, all-rac-γ-Tocopherol, DL-γ-Tocopherol
CAS號	7616-22-0
Inchi	InChI=1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3
InchiKey	QUEDXNHFTDJVIY-UHFFFAOYSA-N
分子式 Formula	C28H48O2
分子量 Molecular Weight	416.69
溶解度Solubility
性狀	A solution in hexane
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說明	(±)-γ-Tocopherol(CAS:7616-22-0):僅限應用于工業(yè)或者科學研究過程中非醫(yī)療目的，不應用于人類或動物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。
Introduction	(±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties. It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays. It also reduces the synthesis of prostaglandin E2 (PGE2) induced by LPS in RAW 264.7 macrophages and by IL-1β in A549 cells. (±)-γ-Tocopherol inhibits LPS-induced nitrite release and inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells and reduces COX-2 activity in A549 cells pretreated with IL-1β. Serum levels of (±)-γ-tocopherol are decreased in patients with cardiovascular disease.
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備注

[1]Jiang, Q., Christen, S., Shigenaga, M.K., et al. γ-Tocopherol, the major form of vitamin E in the US diet, deserves more attention. American Journal of Clinical Nutrition 74, 714-722 (2001).2. Cooney, R.V., Franke, A.A., Harwood, P.J., et al. γ-Tocopherol detoxification of nitrogen dioxide: Superiority to α-tocopherol. Proceedings of the National Academy of Sciences of the United States of America 90, 1771-1775 (1993).3. Jiang, Q., Elson-Schwab, I., Courtemanche, C., et al. γ-Tocopherol and its major metabolite, in contrast to α-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells. Proceedings of the National Academy of Sciences of the United States of America 97, 11494-11499 (2000).