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Lipofectin

NMR下載 COA and HPLC MSDS下載
names：
1-Propanaminium, N,N,N-trimethyl-2,3-bis(9-octadecenyloxy)-, chloride, (Z,Z)-, mixt. with (Z,Z)-1-((((2-aminoethoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl di-9-octadecenoate
CAS號(hào)：
128835-92-7
MDL Number：
MF(分子式)： C83H164ClN2O10P MW(分子量)： 1416.65
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Lipofectin
英文別名	Lipofectin;
CAS號(hào)	128835-92-7
Inchi	InChI=1S/C42H84NO2.C41H79NO8P.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-44-41-42(40-43(3,4)5)45-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)50(38-49-51(46,47)48-36-35-42)37-34-39(41(44)45)32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h20-23,42H,6-19,24-41H2,1-5H3;17-20,39H,3-16,21-38,42H2,1-2H3,(H,44,45)(H,46,47);1H/q+1;;-1/b22-20-,23-21+;19-17-,20-18+;/t42-;39-;/m00./s1
InchiKey	MQFKYWPPAXNQCG-OCNHPIIDSA-N
分子式 Formula	C83H164ClN2O10P
分子量 Molecular Weight	1416.65
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Lipofectin(CAS:128835-92-7):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Lipofectin is a mixture of two cationic lipids, N-[1-(2,3-dioleyloxy)propyl]-n,n,n-trimethylammonium chloride (DOTMA) and dioleoyl phosphotidylethanolamine (DOPE), and has been commonly used to promote transfection of plasmid vectors in vitro and in vivo.
Application1
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Application3

警示圖
危險(xiǎn)性	Warning
危險(xiǎn)性警示
安全聲明
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備注

[1]Pisetsky DS, Reich CF 3rd. The influence of lipofectin on the in vitro stimulation of murine spleen cells by bacterial DNA and plasmid DNA vectors. J Interferon Cytokine Res. 1999 Oct;19(10):1219-26. PubMed PMID: 10547162.

[2]Karikó K, Megyeri K, Xiao Q, Barnathan ES. Lipofectin-aided cell delivery of ribozyme targeted to human urokinase receptor mRNA. FEBS Lett. 1994 Sep 19;352(1):41-4. PubMed PMID: 7925939.

[3] Yeoman LC, Danels YJ, Lynch MJ. Lipofectin enhances cellular uptake of antisense DNA while inhibiting tumor cell growth. Antisense Res Dev. 1992 Spring;2(1):51-9. PubMed PMID: 1422086.

[4] Lambert G, Fattal E, Brehier A, Feger J, Couvreur P. Effect of polyisobutylcyanoacrylate nanoparticles and lipofectin loaded with oligonucleotides on cell viability and PKC alpha neosynthesis in HepG2 cells. Biochimie. 1998 Dec;80(12):969-76. PubMed PMID: 9924975.

[5] Wu X, Cao C, Kumar VS, Cui W. An innovative technique for inoculating recombinant baculovirus into the silkworm Bombyx mori using lipofectin. Res Microbiol. 2004 Jul-Aug;155(6):462-6. PubMed PMID: 15249063.

6: Mazur W, Ali NM, Grinstead WC, Schulz DG, Raizner AE, French BA. Lipofectin-mediated versus adenovirus-mediated gene transfer in vitro and in vivo: comparison of canine and porcine model systems. Coron Artery Dis. 1994 Sep;5(9):779-86. PubMed PMID: 7858769.7: Innes CL, Smith PB, Langenbach R, Tindall KR, Boone LR. Cationic liposomes (Lipofectin) mediate retroviral infection in the absence of specific receptors. J Virol. 1990 Feb;64(2):957-61. PubMed PMID: 2153257; PubMed Central PMCID: PMC249198.8: Omidi Y, Hollins AJ, Benboubetra M, Drayton R, Benter IF, Akhtar S. Toxicogenomics of non-viral vectors for gene therapy: a microarray study of lipofectin- and oligofectamine-induced gene expression changes in human epithelial cells. J Drug Target. 2003 Jul;11(6):311-23. PubMed PMID: 14668052.9: Liu D, Wu J. [Experimental observation of foreign gene transfer with lipofectin to the primary human lens epithelial cells]. Zhonghua Yan Ke Za Zhi. 1998 Sep;34(5):349-51, 23. Chinese. PubMed PMID: 11877223.10: de Fiebre CM, Wu P, Notabartolo D, Millard WJ, Meyer EM. Differential adenoassociated virus vector-driven expression of a neuropeptide Y gene in primary rat brain astroglial cultures after transfection with Sendai virosomes versus Lipofectin. Neurochem Res. 1994 Jun;19(6):643-8. PubMed PMID: 8065520.1

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