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Liothyronine Sodium

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names：
三碘甲狀腺原氨酸鈉; 三碘甲腺原氨酸鈉; 碘塞羅寧鈉; 碘甲腺氨酸鈉; 三碘甲狀腺氨酸鈉
CAS號：
1955-6-1
MDL Number：
MF(分子式)： C15H11I3NNaO4 MW(分子量)： 672.96
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Liothyronine Sodium
英文別名	Liothyronine; Triiodothyronine; 3,3',5-Triiodo-L-thyronine; Liothyronin; Tresitope; 3,5,3'-triiodothyronine; Cytomel; Tertroxin
CAS號	1955-6-1
Inchi	InChI=1S/C15H12I3NO4.Na/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;/h1-4,6,12,20H,5,19H2,(H,21,22);/q;+1/p-1/t12-;/m0./s1
InchiKey	SBXXSUDPJJJJLC-YDALLXLXSA-M
分子式 Formula	C15H11I3NNaO4
分子量 Molecular Weight	672.96
溶解度Solubility
性狀	White to off-white solid powder.
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Liothyronine Sodium(CAS:1955-6-1):僅限應用于工業(yè)或者科學研究過程中非醫(yī)療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Liothyronine is a synthetic form of thyroid hormone (T3) used to treat hypothyroidism and myxedema coma. It is also used as an augmentation strategy in treating Major Depressive Disorder when used in combination with antidepressants. It is marketed as the sodium salt under the brand name Cytomel (or Tertroxin in Australia).
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護
備注

[1]Jonklaas J, Burman KD. Daily Administration of Short-Acting Liothyronine Is Associated with Significant Triiodothyronine Excursions and Fails to Alter Thyroid-Responsive Parameters. Thyroid. 2016 Apr 28. [Epub ahead of print] PubMed PMID: 27030088.

[2]Trimboli P, Centanni M, Virili C. Liquid liothyronine to obtain target TSH in differentiated thyroid cancer patients. Endocr J. 2016 Mar 18. [Epub ahead of print] PubMed PMID: 27000530.

[3] Leese GP, Soto-Pedre E, Donnelly LA. Liothyronine use in a 17 year observational population-based study - The tears study. Clin Endocrinol (Oxf). 2016 Mar 4. doi: 10.1111/cen.13052. [Epub ahead of print] PubMed PMID: 26940864.

[4] Maruo Y, Mori A, Morioka Y, Sawai C, Mimura Y, Matui K, Takeuchi Y. Successful every-other-day liothyronine therapy for severe resistance to thyroid hormone beta with a novel THRB mutation; case report. BMC Endocr Disord. 2016 Jan 12;1

6:1. doi: 10.1186/s12902-015-0081-7. PubMed PMID: 26754848; PubMed Central PMCID: PMC4709977.

5: Foeller ME, Silver RM. Combination Levothyroxine + Liothyronine Treatment in Pregnancy. Obstet Gynecol Surv. 2015 Sep;70(9):584-6. doi: 10.1097/OGX.0000000000000217. PubMed PMID: 26403562.

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