无码人妻专区免费视频,99久久精品国产成人综合

Lactimidomycin

NMR下載 COA and HPLC MSDS下載
names：
4-((E)-2-hydroxy-5-methyl-7-((4E,6Z,10Z)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl)-4-oxooct-6-en-1-yl)piperidine-2,6-dione
CAS號(hào)：
134869-15-1
MDL Number：
MF(分子式)： C26H35NO6 MW(分子量)： 457.56
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

貨品編碼	規(guī)格	純度	價(jià)格 (￥)	現(xiàn)價(jià)(￥)	特價(jià)(￥)	庫存描述	數(shù)量	總計(jì) (￥)

大包裝詢價(jià) 提供各種包裝，敬請(qǐng)垂詢
收藏商品商品點(diǎn)評(píng) 加入購物車立即購買

快速詢價(jià)

收起

你想詢價(jià)的產(chǎn)品

*產(chǎn)品名稱：

CAS號(hào)：

產(chǎn)品編號(hào)：

需求描述：

請(qǐng)準(zhǔn)確填寫您的聯(lián)系方式，以便為您提供最好的服務(wù)。

*公司名稱：

*電子郵箱：

聯(lián)系人：

*電話：

*驗(yàn)證碼：

詢價(jià)

中文別名	Lactimidomycin
英文別名	Lactimidomycin;
CAS號(hào)	134869-15-1
Inchi	InChI=1S/C26H35NO6/c1-17-10-8-6-4-5-7-9-11-25(32)33-26(17)19(3)12-18(2)22(29)16-21(28)13-20-14-23(30)27-24(31)15-20/h4,6,8-12,17-18,20-21,26,28H,5,7,13-16H2,1-3H3,(H,27,30,31)/b6-4-,10-8+,11-9-,19-12+
InchiKey	OYOKHBHOTQDIPM-DXTDVJPQSA-N
分子式 Formula	C26H35NO6
分子量 Molecular Weight	457.56
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說明	Lactimidomycin(CAS:134869-15-1):僅限應(yīng)用于工業(yè)或者科學(xué)研究過程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。
Introduction	Lactimidomycin is a glutarimide antibiotic isolated from Streptomyces amphibiosporus.
Application1
Application2
Application3

警示圖
危險(xiǎn)性	Warning
危險(xiǎn)性警示
安全聲明
安全防護(hù)
備注

[1]Larsen BJ, Sun Z, Lachacz E, Khomutnyk Y, Soellner MB, Nagorny P. Synthesis and Biological Evaluation of Lactimidomycin and Its Analogues. Chemistry. 2015 Dec 21;21(52):19159-67. doi: 10.1002/chem.201503527. Epub 2015 Nov 18. PubMed PMID: 26577990.

[2]Li W, Georg GI. A concise formal total synthesis of lactimidomycin. Chem Commun (Camb). 2015 May 21;51(41):8634-6. doi: 10.1039/c5cc02571k. PubMed PMID: 25900419.

[3] Nagasawa T, Kuwahara S. Formal total synthesis of lactimidomycin. Org Lett. 2013 Jun 21;15(12):3002-5. doi: 10.1021/ol401214f. Epub 2013 Jun 3. PubMed PMID: 23731346.

[4] Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, Merrick WC, Green R, Shen B, Liu JO. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nat Chem Biol. 2010 Mar;6(3):209-217. Epub 2010 Jan 31. PubMed PMID: 20118940; PubMed Central PMCID: PMC2831214.

[5] Larsen BJ, Sun Z, Nagorny P. Synthesis of eukaryotic translation elongation inhibitor lactimidomycin via Zn(II)-mediated Horner-Wadsworth-Emmons macrocyclization. Org Lett. 2013 Jun 21;15(12):2998-3001. doi: 10.1021/ol401186f. Epub 2013 Jun 3. PubMed PMID: 23731327.

6: Seo JW, Ma M, Kwong T, Ju J, Lim SK, Jiang H, Lohman JR, Yang C, Cleveland J, Zazopoulos E, Farnet CM, Shen B. Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues. Biochemistry. 2014 Dec 16;53(49):7854-65. doi: 10.1021/bi501396v. Epub 2014 Dec 1. PubMed PMID: 25405956; PubMed Central PMCID: PMC4270375.7: Micoine K, Persich P, Llaveria J, Lam MH, Maderna A, Loganzo F, Fürstner A. Total syntheses and biological reassessment of lactimidomycin, isomigrastatin and congener glutarimide antibiotics. Chemistry. 2013 Jun 3;19(23):7370-83. doi: 10.1002/chem.201300393. Epub 2013 Apr 17. PubMed PMID: 23595541.8: Garreau de Loubresse N, Prokhorova I, Holtkamp W, Rodnina MV, Yusupova G, Yusupov M. Structural basis for the inhibition of the eukaryotic ribosome. Nature. 2014 Sep 25;513(7519):517-22. doi: 10.1038/nature13737. Epub 2014 Sep 10. PubMed PMID: 25209664.9: Carocci M, Yang PL. Lactimidomycin is a broad-spectrum inhibitor of dengue and other RNA viruses. Antiviral Res. 2016 Apr;128:57-62. doi: 10.1016/j.antiviral.2016.02.005. Epub 2016 Feb 10. PubMed PMID: 26872864; PubMed Central PMCID: PMC4850914.10: Zhang B, Yang D, Yan Y, Pan G, Xiang W, Shen B. Overproduction of lactimidomycin by cross-overexpression of genes encoding Streptomyces antibiotic regulatory proteins. Appl Microbiol Biotechnol. 2016 Mar;100(5):2267-77. doi: 10.1007/s00253-015-7119-7. Epub 2015 Nov 10. PubMed PMID: 26552797; PubMed Central PMCID: PMC4758858.1

對(duì)不起，暫無產(chǎn)品評(píng)價(jià)！

MSDS

SDS 1.0 中文

展開

SDS 1.0 英文

展開