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Kokusaginine

NMR下載 COA and HPLC MSDS下載
names：
Furo(2,3-b)quinoline, 4,6,7-trimethoxy-
CAS號：
484-08-2
MDL Number：
MF(分子式)： C14H13NO4 MW(分子量)： 259.26
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Kokusaginine
英文別名	Kokusaginine; Kokusaginin;
CAS號	484-08-2
Inchi	InChI=1S/C14H13NO4/c1-16-11-6-9-10(7-12(11)17-2)15-14-8(4-5-19-14)13(9)18-3/h4-7H,1-3H3
InchiKey	JBRXRVFXQIKPEA-UHFFFAOYSA-N
分子式 Formula	C14H13NO4
分子量 Molecular Weight	259.26
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說明	Kokusaginine(CAS:484-08-2):僅限應(yīng)用于工業(yè)或者科學(xué)研究過程中非醫(yī)療目的，不應(yīng)用于人類或動物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。
Introduction	Kokusaginine is an antimalarial alkaloid from Teclea afzelii.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護(hù)
備注

[1]Bowen IH, Motawe HM. Isolation and Identification of Kokusaginine from Tinospora malabarica. Planta Med. 1985 Dec;51(6):529-30. PubMed PMID: 17345283.

[2]Wahyuni TS, Widyawaruyanti A, Lusida MI, Fuad A, Soetjipto, Fuchino H, Kawahara N, Hayashi Y, Aoki C, Hotta H. Inhibition of hepatitis C virus replication by chalepin and pseudane IX isolated from Ruta angustifolia leaves. Fitoterapia. 2014 Dec;99:276-83. doi: 10.1016/j.fitote.2014.10.011. Epub 2014 Oct 22. PubMed PMID: 25454460.

[3] Sichaem J, Rojpitikul T, Sawasdee P, Lugsannangarm K, Santi TP. Furoquinoline Alkaloids from the Leaves of Evodia lepta as Potential Cholinesterase Inhibitors and their Molecular Docking. Nat Prod Commun. 2015 Aug;10(8):1359-62. PubMed PMID: 26434116.

[4] Astelbauer F, Gruber M, Brem B, Greger H, Obwaller A, Wernsdorfer G, Congpuong K, Wernsdorfer WH, Walochnik J. Activity of selected phytochemicals against Plasmodium falciparum. Acta Trop. 2012 Aug;123(2):96-100. doi: 10.1016/j.actatropica.2012.04.002. Epub 2012 Apr 17. PubMed PMID: 22537982.

[5] Cheng JT, Chang TK, Chen IS. Skimmianine and related furoquinolines function as antagonists of 5-hydroxytryptamine receptors in animals. J Auton Pharmacol. 1994 Oct;14(5):365-74. PubMed PMID: 7829541.

6: Hanawa F, Fokialakis N, Skaltsounis AL. Photo-activated DNA binding and antimicrobial activities of furoquinoline and pyranoquinolone alkaloids from rutaceae. Planta Med. 2004 Jun;70(6):531-5. PubMed PMID: 15229804.7: Wansi JD, Hussain H, Tcho AT, Kouam SF, Specht S, Sarite SR, Hoerauf A, Krohn K. Antiplasmodial activities of furoquinoline alkaloids from Teclea afzelii. Phytother Res. 2010 May;24(5):775-7. doi: 10.1002/ptr.2894. PubMed PMID: 19496062.8: Chen KS, Chang YL, Teng CM, Chen CF, Wu YC. Furoquinolines with antiplatelet aggregation activity from leaves of Melicope confusa. Planta Med. 2000 Feb;66(1):80-1. PubMed PMID: 10705744.9: Richardson JS, Sethi G, Lee GS, Malek SN. Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cells. BMC Complement Altern Med. 2016 Oct 12;16(1):389. PubMed PMID: 27729078; PubMed Central PMCID: PMC5059921.10: Sandjo LP, Kuete V, Tchangna RS, Efferth T, Ngadjui BT. Cytotoxic Benzophenanthridine and Furoquinoline Alkaloids from Zanthoxylum buesgenii (Rutaceae). Chem Cent J. 2014 Oct 21;8(1):61. doi: 10.1186/s13065-014-0061-4. eCollection 2014. PubMed PMID: 25349626; PubMed Central PMCID: PMC4207896.1

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