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Karounidiol

NMR下載 COA and HPLC MSDS下載
names：
(3R,4aR,6bS,8aS,11R,12aR,12bS,14bR)-11-(hydroxymethyl)-4,4,6b,8a,11,12b,14b-heptamethyl-1,2,3,4,4a,5,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicen-3-ol
CAS號：
118117-31-0
MDL Number：
MF(分子式)： C30H48O2 MW(分子量)： 440.71
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Karounidiol
英文別名	CCRIS7117; CCRIS-7117; CCRIS 7117;
CAS號	118117-31-0
Inchi	InChI=1S/C30H48O2/c1-25(2)22-9-8-21-20(28(22,5)12-11-24(25)32)10-13-30(7)23-18-26(3,19-31)14-15-27(23,4)16-17-29(21,30)6/h8,10,22-24,31-32H,9,11-19H2,1-7H3/t22-,23+,24+,26+,27+,28-,29+,30-/m0/s1
InchiKey	UIXJVDGAGQPTFR-HJOMSTLHSA-N
分子式 Formula	C30H48O2
分子量 Molecular Weight	440.71
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Karounidiol(CAS:118117-31-0):僅限應用于工業(yè)或者科學研究過程中非醫(yī)療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Karounidiol is a bioactive chemical with cytotoxic activity.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護
備注

[1]Yasukawa K, Akihisa T, Tamura T, Takido M. Inhibitory effect of karounidiol on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion. Biol Pharm Bull. 1994 Mar;17(3):460-2. PubMed PMID: 8019519.

[2]Akihisa T, Tokuda H, Ichiishi E, Mukainaka T, Toriumi M, Ukiya M, Yasukawa K, Nishino H. Anti-tumor promoting effects of multiflorane-type triterpenoids and cytotoxic activity of karounidiol against human cancer cell lines. Cancer Lett. 2001 Nov 8;173(1):9-14. PubMed PMID: 11578803.

[3] Akihisa T, Kokke WC, Tamura T, Nambara T. 7-Oxodihydrokarounidiol [7-oxo-D:C-friedo-olean-8-ene-3 alpha,29-diol], a novel triterpene from Trichosanthes kirilowii. Chem Pharm Bull (Tokyo). 1992 May;40(5):1199-202. PubMed PMID: 1394634.

[4] Wu XY, Chao ZM, Wang C, Tan ZG, Sun W. [Chemical constituents contained in fatty oil from seeds of Cucumis sativus]. Zhongguo Zhong Yao Za Zhi. 2012 Nov;37(21):3252-5. Chinese. PubMed PMID: 23397724.

[5] Ukiya M, Akihisa T, Tokuda H, Toriumi M, Mukainaka T, Banno N, Kimura Y, Hasegawa J, Nishino H. Inhibitory effects of cucurbitane glycosides and other triterpenoids from the fruit of Momordica grosvenori on epstein-barr virus early antigen induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate. J Agric Food Chem. 2002 Nov 6;50(23):6710-5. PubMed PMID: 12405766.

6: Xi YB, Chao ZM, Wang J. [Chemical constituents in unsaponifiable matter from seeds of Trichosanthes hupehensis]. Zhongguo Zhong Yao Za Zhi. 2007 Nov;32(21):2262-5. Chinese. PubMed PMID: 18309669.7: Akihisa T, Ogihara J, Kato J, Yasukawa K, Ukiya M, Yamanouchi S, Oishi K. Inhibitory effects of triterpenoids and sterols on human immunodeficiency virus-1 reverse transcriptase. Lipids. 2001 May;36(5):507-12. PubMed PMID: 11432464.8: Kan LD, Hu Q, Chao ZM, Song X, Cao XL. [Chemical constituents of unsaponifiable matter from seed oil of Momordica cochinchinensis]. Zhongguo Zhong Yao Za Zhi. 2006 Sep;31(17):1441-4. Chinese. PubMed PMID: 17087086.

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