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Kahweol oleate

NMR下載 COA and HPLC MSDS下載
names：
((3bR,5aS,7S,8S,10aS,10bR)-7-hydroxy-10b-methyl-3b,4,5,6,7,8,9,10,10a,10b-decahydro-5a,8-methanocyclohepta[5,6]naphtho[2,1-b]furan-7-yl)methyl oleate
CAS號(hào)：
108214-30-8
MDL Number：
MF(分子式)： C38H58O4 MW(分子量)： 578.87
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Kahweol oleate
英文別名	Kahweol oleate
CAS號(hào)	108214-30-8
Inchi	InChI=1S/C38H58O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-35(39)42-29-38(40)28-37-25-21-32-31-23-26-41-33(31)22-24-36(32,2)34(37)20-19-30(38)27-37/h10-11,22-24,26,30,32,34,40H,3-9,12-21,25,27-29H2,1-2H3/b11-10-/t30-,32-,34+,36-,37-,38+/m0/s1
InchiKey	MDXDAWWJXQHCAA-RWDNSPHTSA-N
分子式 Formula	C38H58O4
分子量 Molecular Weight	578.87
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Kahweol oleate(CAS:108214-30-8):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類(lèi)或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Kahweol oleate is emi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1 induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress.
Application1
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危險(xiǎn)性	Warning
危險(xiǎn)性警示
安全聲明
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[1]Moeenfard M, Erny GL, Alves A. Variability of some diterpene esters in coffee beverages as influenced by brewing procedures. J Food Sci Technol. 2016 Nov;53(11):3916-3927. doi: 10.1007/s13197-016-2378-6. Epub 2016 Nov 7. PubMed PMID: 28035147; PubMed Central PMCID: PMC5156634.

[2]Rustan AC, Halvorsen B, Huggett AC, Ranheim T, Drevon CA. Effect of coffee lipids (cafestol and kahweol) on regulation of cholesterol metabolism in HepG2 cells. Arterioscler Thromb Vasc Biol. 1997 Oct;17(10):2140-9. PubMed PMID: 9351383.

[3] Halvorsen B, Ranheim T, Nenseter MS, Huggett AC, Drevon CA. Effect of a coffee lipid (cafestol) on cholesterol metabolism in human skin fibroblasts. J Lipid Res. 1998 Apr;39(4):901-12. PubMed PMID: 9555953.

[4] Ranheim T, Halvorsen B, Huggett AC, Blomhoff R, Drevon CA. Effect of a coffee lipid (cafestol) on regulation of lipid metabolism in CaCo-2 cells. J Lipid Res. 1995 Oct;36(10):2079-89. PubMed PMID: 8576635.

[5] D'Amelio N, De Angelis E, Navarini L, Schievano E, Mammi S. Green coffee oil analysis by high-resolution nuclear magnetic resonance spectroscopy. Talanta. 2013 Jun 15;110:118-27. doi: 10.1016/j.talanta.2013.02.024. Epub 2013 Mar 4. PubMed PMID: 23618184.

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