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Eptazocine hydrobromide

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names：
1,4-dimethyl-2,3,4,5,6,7-hexahydro-1H-1,6-methanobenzo[e]azonin-10-ol hydrobromide
CAS號：
72150-17-5
MDL Number：
MF(分子式)： C15H22BrNO MW(分子量)： 312.25
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Eptazocine hydrobromide
英文別名	Eptazocine hydrobromide; l-ST-2121; MCV 4169; ST-2121; sT 2121, l-; MCV-4169; MCV4169;
CAS號	72150-17-5
Inchi	InChI=1S/C15H21NO.BrH/c1-15-5-6-16(2)10-11(9-15)7-12-3-4-13(17)8-14(12)15;/h3-4,8,11,17H,5-7,9-10H2,1-2H3;1H
InchiKey	KMISFPIWSMSMJD-UHFFFAOYSA-N
分子式 Formula	C15H22BrNO
分子量 Molecular Weight	312.25
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說明	Eptazocine hydrobromide(CAS:72150-17-5):僅限應用于工業(yè)或者科學研究過程中非醫(yī)療目的，不應用于人類或動物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。
Introduction	Eptazocine hydrobromide is a DG01564 Opioid receptor agonist, DG01562 kappa-Opioid receptor agonist, DG01984 Opioid analgesics, DG01586 Opioid receptor antagonist.
Application1
Application2
Application3

警示圖
危險性	Warning
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[1]Mizobe T, Oda Y, Natsuyama T, Miyazaki M. Anesthetic management with eptazocine hydrobromide in patients receiving long-term antipsychotic medication. J Anesth. 1992 Jan;6(1):21-7. PubMed PMID: 15278579.

[2]Yanaura S, Kitagawa H, Hosokawa T, Misawa M. [Effects of methanobenzazonine (2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine) derivatives on the cough reflex and respiration]. Nihon Yakurigaku Zasshi. 1982 Jul;80(1):43-50. Japanese. PubMed PMID: 7173733.

[3] Koizumi T, Kakemi M, Katayama K, Ogawa M. A pharmcokinetic model for enterohepatic circulation of an analgesic l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121) in rats. J Pharmacobiodyn. 1981 Jul;4(7):461-8. PubMed PMID: 7299614.

[4] Ogawa M, Nogami Y, Miyamura Y, Kameda S, Tsuji S, Miyamura Y, Miyamoto S, Koizumi T. [Metabolic fate of a new analgesics l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121). III.) Absorption, excretion and metabolism in mouse rat, rabbit, dog, monkey and man (author's transl)]. Yakugaku Zasshi. 1980 Sep;100(9):967-72. Japanese. PubMed PMID: 7218159.

[5] Futsukaichi O, Hayashi I, Miyamura Y, Kurobe A, Nozawa T, Miyamoto S, Shiotani S. [Synthesis and analgesic activities of urinary metabolites of a new analgesic (-)-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121) in rats (author's transl)]. Yakugaku Zasshi. 1980 May;100(5):509-14. Japanese. PubMed PMID: 7452444.

6: Suzuki T, Izumisawa Y, Nozawa T, Yanaura S. [Physical dependence liability test of l-1, 4-dimethyl-10-hydroxy-2, 3, 4, 5, 6, 7-hexahydro-1, 6-methano-1H-4-benzazonine hydrobromide (l-ST-2121) in rats (author's transl)]. J Toxicol Sci. 1980 May;5(2):163-76. Japanese. PubMed PMID: 7192746.7: Nogami Y, Miyamura Y, Kurobe A, Ogawa M, Miyamoto S, Koizumi T. [Metabolic fate of a new analgesics 1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (ST-2121). II. Comparative metabolism of the optical isomers in rat urine (author's transl)]. Yakugaku Zasshi. 1980 Apr;100(4):407-14. Japanese. PubMed PMID: 7431213.8: Nogami Y, Futsukaichi O, Ogawa M, Koizumi T. [Metabolic fate of a new analgesics l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121). I. Absorption, distribution and excretion of l-ST-2121 in rats (author's transl)]. Yakugaku Zasshi. 1979 Jul;99(7):757-64. Japanese. PubMed PMID: 583639.

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