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Di-O-methylamentoflavone

NMR下載 COA and HPLC MSDS下載
names：
4H-1-Benzopyran-4-one, 8-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-, dimethyl ether
CAS號(hào)：
41583-84-0
MDL Number：
MF(分子式)： C32H22O10 MW(分子量)： 566.52
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Di-O-methylamentoflavone
英文別名	Amentoflavone dimethyl ether, Di-O-methylamentoflavone
CAS號(hào)	41583-84-0
Inchi	1S/C32H22O10/c1-39-18-6-3-15(4-7-18)25-13-23(37)31-24(38)14-27(40-2)29(32(31)42-25)19-9-16(5-8-20(19)34)26-12-22(36)30-21(35)10-17(33)11-28(30)41-26/h3-14,33-35,38H,1-2H3
InchiKey	SQGLUEWZRKIEGS-UHFFFAOYSA-N
分子式 Formula	C32H22O10
分子量 Molecular Weight	566.52
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Di-O-methylamentoflavone(CAS:41583-84-0):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類(lèi)或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Di-O-methylamentoflavone is a 3,5-cyclic nucleotide phosphodiesterase inhibitor. It has anti-angiogenic and anti-metastatic effects.
Application1
Application2
Application3

警示圖
危險(xiǎn)性	Warning
危險(xiǎn)性警示
安全聲明
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[1]Chen JH, Chen WL, Liu YC. Amentoflavone Induces Anti-angiogenic and Anti-metastatic Effects Through Suppression of NF-κB Activation in MCF-7 cells. Anticancer Res. 2015 Dec;35(12):6685-93. PubMed PMID: 26637885.

[2]Zha X, Xu Z, Liu Y, Xu L, Huang H, Zhang J, Cui L, Zhou C, Xu D. Amentoflavone enhances osteogenesis of human mesenchymal stem cells through JNK and p38 MAPK pathways. J Nat Med. 2016 Jul;70(3):634-44. doi: 10.1007/s11418-016-0993-1. Epub 2016 Apr 22. PubMed PMID: 27106512.

[3] Zhang Z, Sun T, Niu JG, He ZQ, Liu Y, Wang F. Amentoflavone protects hippocampal neurons: anti-inflammatory, antioxidative, and antiapoptotic effects. Neural Regen Res. 2015 Jul;10(7):1125-33. doi: 10.4103/1673-5374.160109. PubMed PMID: 26330838; PubMed Central PMCID: PMC4541246.

[4] Yang Y, Xu W, Peng K, Sun X. [Amentoflavone induces apoptosis in SW480 human colorectal cancer cells via regulating β-catenin and caspase-3 expressions]. Nan Fang Yi Ke Da Xue Xue Bao. 2014 Jun;34(7):1035-8. Chinese. PubMed PMID: 25057079.

[5] Hwang JH, Choi H, Woo ER, Lee DG. Antibacterial effect of amentoflavone and its synergistic effect with antibiotics. J Microbiol Biotechnol. 2013;23(7):953-8. PubMed PMID: 23727809.

6: Lee JS, Sul JY, Park JB, Lee MS, Cha EY, Song IS, Kim JR, Chang ES. Fatty acid synthase inhibition by amentoflavone suppresses HER2/neu (erbB2) oncogene in SKBR3 human breast cancer cells. Phytother Res. 2013 May;27(5):713-20. doi: 10.1002/ptr.4778. Epub 2012 Jul 5. PubMed PMID: 22767439.7: Xu P, Jiang EJ, Wen SY, Lu DD. Amentoflavone acts as a radioprotector for irradiated v79 cells by regulating reactive oxygen species (ROS), cell cycle and mitochondrial mass. Asian Pac J Cancer Prev. 2014;15(18):7521-6. PubMed PMID: 25292022.8: Sakthivel KM, Guruvayoorappan C. Amentoflavone inhibits iNOS, COX-2 expression and modulates cytokine profile, NF-κB signal transduction pathways in rats with ulcerative colitis. Int Immunopharmacol. 2013 Nov;17(3):907-16. doi: 10.1016/j.intimp.2013.09.022. Epub 2013 Oct 12. PubMed PMID: 24126114.9: Oh J, Rho HS, Yang Y, Yoon JY, Lee J, Hong YD, Kim HC, Choi SS, Kim TW, Shin SS, Cho JY. Extracellular signal-regulated kinase is a direct target of the anti-inflammatory compound amentoflavone derived from Torreya nucifera. Mediators Inflamm. 2013;201

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