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Diodone

NMR下載 COA and HPLC MSDS下載
names：
1(4H)-Pyridineacetic acid, 3,5-diiodo-4-oxo-, compd. with 2,2'-iminobis(ethanol) (11)
CAS號(hào)：
300-37-8
MDL Number：
MF(分子式)： C11H16I2N2O5 MW(分子量)： 510.0669
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Diodone
英文別名	Diodone, Iodopyracet
CAS號(hào)	300-37-8
Inchi	InChI=1S/C7H5I2NO3.C4H11NO2/c8-4-1-10(3-6(11)12)2-5(9)7(4)13;6-3-1-5-2-4-7/h1-2H,3H2,(H,11,12);5-7H,1-4H2
InchiKey	RERHJVNYJKZHLJ-UHFFFAOYSA-N
分子式 Formula	C11H16I2N2O5
分子量 Molecular Weight	510.0669
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Diodone(CAS:300-37-8):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類(lèi)或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Diodone is an ionic monomeric contrast medium that was formerly used for a variety of diagnostic procedures.
Application1
Application2
Application3

警示圖
危險(xiǎn)性	Warning
危險(xiǎn)性警示
安全聲明
安全防護(hù)
備注

[1]Russel FG, Wouterse AC, Van Ginneken CA. Physiologically based pharmacokinetic model for the renal clearance of iodopyracet and the interaction with probenecid in the dog. Biopharm Drug Dispos. 1989 Mar-Apr;10(2):137-52. PubMed PMID: 2706315.

[2]Wang N, Xu Q, Duan S, Lei R, Guo J. [Evaluation of risk factors and prognosis on diodone-induced acute kidney injury according to ESUR and KDIGO criteria]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016 Jan;41(1):65-70. doi: 10.11817/j.issn.1672-7347.2016.01.010. Chinese. PubMed PMID: 26819427.

[3] Burg MB, Weller PF. Iodopyracet transport by isolated perfused flounder proximal renal tubules. Am J Physiol. 1969 Oct;217(4):1053-6. PubMed PMID: 5824304.

[4] Hekman P, van Ginneken CA. Kinetic modeling of the renal excretion of iodopyracet in the dog. J Pharmacokinet Biopharm. 1982 Feb;10(1):77-92. PubMed PMID: 7069579.

[5] Maher FT, Tauxe WN, Strong CG, Elveback LR. Renal clearance in man of pharmaceuticals containing radioactive iodine: influence of added carrier iodopyracet or o-iodohippurate. Mayo Clin Proc. 1970 Oct;45(10):701-11. PubMed PMID: 5479145.

6: FORBES M, BECKER B. The transport of organic anions by the rabbit eye. II. In vivo transport of iodopyracet (Diodrast). Am J Ophthalmol. 1960 Nov;50:867-75. PubMed PMID: 13700701.7: Shikano N, Kanai Y, Kawai K, Ishikawa N, Endou H. Transport of 99mTc-MAG3 via rat renal organic anion transporter 1. J Nucl Med. 2004 Jan;45(1):80-5. PubMed PMID: 14734677.8: Katayama K, Ohtani H, Kawabe T, Mizuno H, Endoh M, Kakemi M, Koizumi T. Kinetic studies on drug disposition in rabbits. I. Renal excretion of iodopyracet and sulfamethizole. J Pharmacobiodyn. 1990 Feb;13(2):97-107. PubMed PMID: 2384854.9: Misson RT, Cutler RE. Radiocontrast-induced renal failure. West J Med. 1985 May;142(5):657-64. PubMed PMID: 4013281; PubMed Central PMCID: PMC1306134.10: Katayama K, Tsubota E, Endoh M, Kakemi M, Koizumi T. Effect of iodopyracet on renal excretion of sulfamethizole in rabbits. J Pharmacobiodyn. 1990 Mar;13(3):179-85. PubMed PMID: 2374087.1

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