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Albifylline

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names：
1-(5-hydroxy-5-methylhexyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
CAS號(hào)：
107767-55-5
MDL Number：
MF(分子式)： C13H20N4O3 MW(分子量)： 280.33
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Albifylline
英文別名	Albifylline
CAS號(hào)	107767-55-5
Inchi	InChI=1S/C13H20N4O3/c1-13(2,20)6-4-5-7-17-11(18)9-10(15-8-14-9)16(3)12(17)19/h8,20H,4-7H2,1-3H3,(H,14,15)
InchiKey	NWXULHNEYYFVMF-UHFFFAOYSA-N
分子式 Formula	C13H20N4O3
分子量 Molecular Weight	280.33
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Albifylline(CAS:107767-55-5):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Albifylline is a xanthine derivates and anti-asthmatic agent. It may cause a significant reduction of shock-induced leukocyte adhesions to the sinusoidal endothelium in the liver after hemorrhagic shock. In addition, it improves microvascular blood flow in the liver.
Application1
Application2
Application3

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危險(xiǎn)性	Warning
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[1]Marzi I, Maier M, Herzog C, Bauer M. Influence of pentoxifylline and albifylline on liver microcirculation and leukocyte adhesion after hemorrhagic shock in the rat. J Trauma. 1996 Jan;40(1):90-6. PubMed PMID: 8577006.

[2]Meskini N, Némoz G, Okyayuz-Baklouti I, Lagarde M, Prigent AF. Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation. Biochem Pharmacol. 1994 Mar 2;47(5):781-8. PubMed PMID: 8135854.

[3] Sinha B, Semmler J, Eisenhut T, Eigler A, Endres S. Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids. Eur J Immunol. 1995 Jan;25(1):147-53. PubMed PMID: 7843225.

[4] Sinha B, Semmler J, Haen E, Moeller J, Endres S. Radioimmunoassays for cyclic AMP cross-react with phosphodiesterase inhibitors and buffer components. J Toxicol Methods. 1995 Sep;34(1):29-36. PubMed PMID: 7496044.

[5] Hand WL, Hand DL. Influence of pentoxifylline and its derivatives on antibiotic uptake and superoxide generation by human phagocytic cells. Antimicrob Agents. 1995 Jul;39(7):1574-9. PubMed PMID: 7492107; PubMed Central PMCID: PMC162784.

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