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Aspartyl adenylate

NMR下載 COA and HPLC MSDS下載
names：
(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-((phosphonooxy)methyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-L-aspartic acid
CAS號(hào)：
19046-78-7
MDL Number：
MF(分子式)： C14H18N5O11P MW(分子量)： 463.29
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Aspartyl adenylate
英文別名	Aspartyl adenylate;
CAS號(hào)	19046-78-7
Inchi	InChI=1S/C14H18N5O11P/c20-7(21)1-5(14(24)25)18-11-8-12(16-3-15-11)19(4-17-8)13-10(23)9(22)6(30-13)2-29-31(26,27)28/h3-6,9-10,13,22-23H,1-2H2,(H,20,21)(H,24,25)(H,15,16,18)(H2,26,27,28)/t5-,6+,9+,10+,13+/m0/s1
InchiKey	OFBHPPMPBOJXRT-VWJPMABRSA-N
分子式 Formula	C14H18N5O11P
分子量 Molecular Weight	463.29
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Aspartyl adenylate(CAS:19046-78-7):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Aspartyl adenylate is the adenyl derivative of succinic acid that plays a part in nucleotide metabolism.
Application1
Application2
Application3

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危險(xiǎn)性	Warning
危險(xiǎn)性警示
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[3] Bantysh O, Serebryakova M, Makarova KS, Dubiley S, Datsenko KA, Severinov K. Enzymatic synthesis of bioinformatically predicted microcin C-like compounds encoded by diverse bacteria. MBio. 2014 May 6;5(3):e01059-14. doi: 10.1128/mBio.01059-14. PubMed PMID: 24803518; PubMed Central PMCID: PMC4010828.

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[5] Gaudry A, Lorber B, Neuenfeldt A, Sauter C, Florentz C, Sissler M. Re-designed N-terminus enhances expression, solubility and crystallizability of mitochondrial protein. Protein Eng Des Sel. 2012 Sep;25(9):473-81. doi: 10.1093/protein/gzs046. Epub 2012 Aug 7. PubMed PMID: 22871419.

6: Agarwal V, Tikhonov A, Metlitskaya A, Severinov K, Nair SK. Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4425-30. doi: 10.1073/pnas.1114224109. Epub 2012 Mar 2. PubMed PMID: 22388748; PubMed Central PMCID: PMC3311384.7: Severinov K, Nair SK. Microcin C: biosynthesis and mechanisms of bacterial resistance. Future Microbiol. 2012 Feb;7(2):281-9. doi: 10.2217/fmb.11.148. Review. PubMed PMID: 22324995; PubMed Central PMCID: PMC3350762.8: Vondenhoff GH, Van Aerschot A. Microcin C: biosynthesis, mode of action, and potential as a lead in antibiotics development. Nucleosides Nucleotides Nucleic Acids. 2011 Jul-Aug;30(7-8):465-74. doi: 10.1080/15257770.2011.583972. PubMed PMID: 21888539.9: Vondenhoff GH, Dubiley S, Severinov K, Lescrinier E, Rozenski J, Van Aerschot A. Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials. Bioorg Med Chem. 2011 Sep 15;19(18):5462-7. doi: 10.1016/j.bmc.2011.07.052. Epub 2011 Aug 3. PubMed PMID: 21855353.10: Polydorides S, Amara N, Aubard C, Plateau P, Simonson T, Archontis G. Computational protein design with a generalized Born solvent model: application to Asparaginyl-tRNA synthetase. Proteins. 2011 Dec;79(12):3448-68. doi: 10.1002/prot.23042. Epub 2011 May 11. PubMed PMID: 21563215.1

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